|Dimensions:||1300 x 2000 pixels|
Audiences: Scientific, Medical
Keywords: serotonin receptorserotonin receptor, 5HT, illustration, image, 3D, PDB, coordinates, receptor, 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D, 5-HT1E, 5-HT1F, 5-HT1A, 5-HT2B, 5-HT2C, 5-HT3, 5-HT4, 5-HT5A, 5-HT6, 5-HT7Order or Customize it
Serotonin (5-hydroxytryptamine, 5-HT) is unique among the monoamines in that its effects are felt by as many as 13 distinct heptahelical, G-protein-coupled receptors (GPCRs) and one ligand-gated ion channel (or more). These receptors are divided into seven distinct classes (5-HT(1) to 5-HT(7)) largely on the basis of their structural and operational characteristics.
Shown here is the general structure of the 5-HT1-class of these GPCR's. This structure is based on a homology model and molecular-dynamics simulation. This illustration represents an accurate look at the the receptor structure.
Other views are available, as well as a rotation-style animation.