The Bacteriorhodopsin D85S Mutant / Single Project

Media Details

Media ID: SYM0037
Client: Scientific
Created on: 2002-05-16
Published on: 2004-04-14
Dimensions: 1217 x 1913 pixels

Type: Infographic

Audiences: Scientific

Keywords: D85S, anion, pump, cubic, lipid, phase, crystallization, 3D, bicontinuous

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  • The Bacteriorhodopsin D85S Mutant


Cover of the Journal of Molecular Biology. The D85S mutant is unique in that its point mutation resulting in the loss of the Schiff Base counterion allows it to pump anions in a direction opposite of proton flow in native BR.

Crystal structure of the D85S mutant of bacteriorhodopsin: model of an O-like photocycle intermediate. Rouhani S, Cartailler JP, Facciotti MT, Walian P, Needleman R, Lanyi JK, Glaeser RM, Luecke H. J Mol Biol. 2001 Oct 26;313(3):615-28.


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